Genetic Testing – Connecticare

Connecticare requires Genetic testing to be pre-authorized

The most common tests requiring pre-authorization include:

1. Cytochrome CYP P450 testing:
   1. CYP 450 2C19
   2. CYP 450 2C9
   3. CYP 450 2D6
   4. Warfarin/Coumadin Sensitivity
2. Hemochromatosis
3. Factor V Leiden
4. Fragile X (with reflex)
5. MTHFR Gene Mutation
6. Ashkenazi Jewish Panel
7. Prothrombin Factor II mutation
8. Antithrombin III Activity
9. Alpha-1 Antitrypsin (AAT)
10. Tay –Sachs (Ashkenazi)
11. Gaucher Disease Mutation
12. Canavan Disease Mutation

The following tests do not require pre-authorization:

1. Routine chromosomal analysis (e.g., peripheral blood, tissue culture, chorionic villous sampling, amniocentesis)
2. DNA testing for cystic fibrosis
3. FISH (fluorescent in situ hybridization) for diagnosis of lymphoma or leukemia

For additional information, please contact: